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• Okayama Plant

  High production capacity in pharmaceuticals and diagnostic reagents, from manufacturing of liquid/solid formulations to the packaging process

  -Pharmaceuticals GMP compliance ^*1
  -ISO13485 certification ^*2

  ^*1 GMP (Good Manufacturing Practice): Manufacturing and quality control of pharmaceuticals, etc.
  ^*2 ISO13485: International standard for quality management systems for medical devices.

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• High production capacity of pharmaceuticals and diagnostic reagents from liquid/solid formulations to the packaging process

  We manufacture high quality products in a strict manufacturing and quality control system which is established in conformity with the GMP requirements ^*1 for pharmaceutical products, and with the international quality management system ISO 13485 ^*2 for diagnostic reagents. In addition to conducting repeated quality tests at each step to determine if a product is ready to be shipped, we also conduct stability testing after shipment of the products. We have succeeded in mass production of immune reagents, and possess solution facilities which enable aseptic manipulation manufacturing.

  At our Okayama plant we aim to further strengthen the manufacturing capacity of high-quality pharmaceutical products, and our manufactu-ring facility for liquid/solid formulations has been in full-scale operation since 2009. In addition to establishing a quality management system to monitor the production line from every different angle, and fully furnishing a clean manufacturing environment to produce the liquid products, we have installed state-of-the-art equipments that are able to meet a variety of needs in producing high quality products.

• Gunma Plant

  -Contract manufacturing^*3
  -PIC/S GMP^*4
  -ISO 14001 certification^*5

  ^*3 Contract manufacturing: Manufacturing products by taking on all or part of the manufacturing process from a contractor.
  ^*4 PIC/S GMP: Manufacturing control and quality control of pharmaceuticals, etc.
  ^*5 ISO 14001 certification: International standard for environmental management systems.

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Contract manufacturing of a wide variety of products with a commitment to quality

Based on its technological capabilities cultivated over many years, the Gunma Plant manufactures ethical and over-the-counter pharmaceuticals and quasi drugs as well as food additives and investigational drugs on a contract basis. Dosage forms include tablets (sugar-coated, film-coated, wet tablets®, etc.) and capsules, as well as granules, dispersions, liquids, and ointments (creams). Packaging formats include PTP (blister packaging), double-sided aluminum PTP packaging, sachets, bottle packaging (polyethylene containers and glass bottles), tube packaging, double-formed packaging, and many others.

Our employees are conscious of “creating quality” with the aim to produce a stable supply of high-quality products while using facilities, equipment, environments, and systems compliant with PIC/S GMP to strictly control quality and manufacturing, from the receipt of raw packaging materials to inspection and shipment of final products.

In 2026, we constructed new facilities for the production of pharmaceuticals and began operations. These facilities have doubled our manufacturing capacity for oral solid dosage forms of small-molecule pharmaceuticals to roughly 3.6 billion tablets per year. They have also allowed for contract manufacturing of anti-cancer and hormone drugs in oral solid dosage forms. We also added a refrigerated warehouse—equipped with functions to ensure product quality—to store antibody drugs and other sterile preparations.

The Gunma Plant prioritizes energy conservation and environmental preservation. As part of our commitment, we obtained ISO 14001 certification in 2001. We also use a central energy monitoring and control system to comprehensively manage energy in the plant. Furthermore, we operate a dedicated purification system that removes impurities from tap water to produce purified water for manufacturing; after use, this water is decomposed by microorganisms and discharged as clean water.

We will continue to fulfill our corporate social responsibilities through various initiatives and contribute to the realization of a sustainable society.

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• Chiba Plant

  The largest surgical suture manufacture, and our production base for various types of medical devices

  -Medical devices QMS ^*6 compliance
  -ISO13485 certification
  -CE marking ^*7 certification

  ^*6 QMS (Quality Management System): Management system to ensure the quality of products and services.
  ^*7 CE Marking: Mark indicating that the products comply with the safety standards of the European Union (EU).

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• The largest surgical suture manufacture, and our production base for various types of medical devices

  Our Chiba plant, with state-of-the-art facilities, is the largest surgical suture manufacturing plant in Japan. It is equipped with integrated systems for the technological development and manufacturing of a variety of medical devices focused on surgical sutures (NESCO sutures), and functional products which are safe and easy to use. We have built a strict quality management system based on the QMS criteria, covering all processes from the arrival of raw materials to manufacturing, packaging, and shipping. In addition, we have enhanced our state-of-the-art testing facilities and conduct tests at four different stages: receiving, in-process, intermediate products, and finished products. Our in-house standards are stricter than the Pharmaceutical Affairs Law and Government standards, and we ship only products which have passed our internal standards out to the market.